Carboxylic acids and derivatives
Medchemexpress LLC DG013A (formate) | 00-00-0 | 99.6% | C27H37N4O4P.2/5CH2O2 | 10MG
DG013A (formate) is a phosphinic acid tripeptide-mimetic inhibitor for research use targeting endoplasmic reticulum aminopeptidases ERAP1 and ERAP2. It is supplied as a powder with molecular formula C27H37N4O4P·2/5CH2O2 and molecular weight 530.99; reported potency values are ERAP1 IC50 = 33 nM and ERAP2 IC50 = 11 nM.
- Phosphinic acid tripeptide-mimetic inhibitor.
- Potent ERAP1 and ERAP2 inhibition (IC50 33 nM and 11 nM).
- High purity (99.6% by LCMS).
- Powder form for easy handling and storage.
- Stable as powder at -20°C for up to 3 years.
- In-solvent stability: -80°C for 6 months, -20°C for 1 month.
Apexbio Technology LLC CA 074 134448-10-5 25mg
CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
Medchemexpress LLC Ephrin-B1/EFNB1 Rat 5ug
Ephrin-B1/EFNB1 proteins bind to Eph receptors on neighboring cells and promote bidirectional signaling in developing neurons blood vessels and epithelia It has high affinity for EPHB1/ELK also binds EPHB2 and EPHB3 and induces commissural axon/growth cone collapse Ephrin-B1/EFNB1 Protein Rat (HEK293 His) is the recombinant rat-derived Ephrin-B1/EFNB1 protein expressed by HEK293 with C-His labeled tag
eMolecules 3-N-DI-BOC-2-METHYL-PROPIONIC ACID | 357610-29-8 | MFCD24475052 | 5g
AstaTech | 3-N-DI-BOC-2-METHYL-PROPIONIC ACID | 5g | 338839279 | 70023 | 95.000 | 357610-29-8 | MFCD24475052 | 303.355 | C14H25NO6
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Cayman Chemical MK886 sodium salt
A potent FLAP antagonist that prevents 5-LO activation in vivo; inhibits LT biosynthesis in leukocytes with an IC50 value of 2.5 nM
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3908218 VINYL CROTONATE 5ML
Medchemexpress LLC Ephrin-B1/EFNB1 Mou 10ug
Ephrin-B1 (EFNB1) protein binds to Eph family receptors enabling signaling between receptor-expressing cells and cells with EFNB1 It is crucial for neuronal axon growth and expressed in various tissues like the adult lung and colon highlighting its widespread presence and importance in mediating cellular interactions Ephrin-B1/EFNB1 Protein Mouse (HEK293 Fc) is the recombinant mouse-derived Ephrin-B1/EFNB1 protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Ephrin-B1/EFNB1 Rat 10ug
Ephrin-B1/EFNB1 proteins bind to Eph receptors on neighboring cells and promote bidirectional signaling in developing neurons blood vessels and epithelia It has high affinity for EPHB1/ELK also binds EPHB2 and EPHB3 and induces commissural axon/growth cone collapse Ephrin-B1/EFNB1 Protein Rat (HEK293 His) is the recombinant rat-derived Ephrin-B1/EFNB1 protein expressed by HEK293 with C-His labeled tag
Cell Signaling Technology Phospho-Cyclin B1 (Ser133) (9E3) Rabbit mAb 20 ul
Phospho-Cyclin B1 (Ser133) (9E3) Rabbit mAb 20 ul
eMolecules Sodium valproate | 1069-66-5 | MFCD00078604 | 25g
Combi-Blocks | Sodium valproate | 25g | 232311152 | QA-1100 | 97.000 | 1069-66-5 | MFCD00078604 | 166.196 | C8H15NaO2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC L-methionine N-(5-(imidazol-5-ylmethylamino)methyl-2'-methylbiphenyl) methyl ester | 344900-92-1 | 99.8% | 466.60 g/mol | C25H30N4O3S | 10MG
FTI-2153 is a potent, highly selective farnesyltransferase inhibitor used as a research reagent to study protein prenylation, Ras processing, and cellular responses to FTase inhibition. The compound is provided with solubility and storage guidance to support preparation of DMSO stocks and in vitro or in vivo formulation workflows.
- Potent FTase inhibition, IC50 1.4 nM.
- Selective inhibition of H-Ras processing in cellular assays.
- Available in small-mass vials and ready-to-use DMSO stock solutions.
- Molecular weight 466.60 g/mol and formula C25H30N4O3S.
- Storage recommended at -20°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO (up to ~90 mg/mL); datasheet provides stock preparation volumes and in vivo formulation options.