Carboxylic acids and derivatives
TARGETMOL CHEMICALS INC Nomifensine maleate 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder. Purity 98.46%
Apexbio Technology LLC CL 316243 disodium salt 151126-84-0 10mg
CL 316243 disodium salt is a small-molecule agonist targeting the 3-adrenergic receptor It is designed to activate 3 receptors thereby modulating lipolytic and thermogenic pathways predominantly in adipose tissues CL 316243 disodium salt exerts its biological activity by selectively binding to 3-adrenergic receptors leading to enhanced adipocyte-mediated lipid metabolism In experimental rodent models administration of CL 316243 increases insulin sensitivity and reduces obesity-related hyperglycemia by promoting glucose uptake primarily in adipose tissue Based on these pharmacological properties CL 316243 disodium salt holds research potential in the study of 3 receptor-mediated metabolic mechanisms and the exploration of therapeutic strategies for metabolic disorders such as obesity and type 2 diabetes
Sigma Aldrich Fine Chemicals Biosciences PF-04634817 succinate >=98% (HPLC) | 1228111-63-4 (free base) | 25MG
PF-04634817 succinate >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 629.67 | 1228111-63-4 (free base) | 25MG
Apexbio Technology LLC L-693,403 maleate 207455-21-8 50mg
L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms
Apexbio Technology LLC 8-CPT-2Me-cAMP, sodium salt 634207-53-7 5mg
8-CPT-2Me-cAMP sodium salt (CAS 634207-53-7) is a selective agonist of exchange proteins directly activated by cAMP (EPACs) which are key intracellular cAMP sensors acting as guanine nucleotide exchange factors for Rap1 and Rap2 This compound effectively activates EPAC1 leading to increased Rap1 activity and enhanced cell adhesion particularly in the presence of MAP1A light chain 2 In Jurkat T cells 8-CPT-2Me-cAMP induces Rap1 activation independently of PKA inhibition In prostate cancer cell models it dose-dependently upregulates Epac1 phosphorylated Akt and stimulates mTORC1/mTORC2 signaling It is widely utilized to dissect EPAC-specific pathways in cell signaling adhesion and proliferation studies
Apexbio Technology LLC NB-598 Maleate 155294-62-5 200mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
TARGETMOL CHEMICALS INC Cloprostenol sodium salt 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water-soluble, crystalline form of cloprostenol compared to the free acid and is a synthetic analog of prostaglandin F2alpha. Purity 98%
eMolecules ChemScene / (Chloromethyl)triethoxysilane / 5g / 536799853 / CS-0086574 / 0.000 / 15267-95-5 / MFCD00039354 / 212.750 / C7H17ClO3Si
ChemScene / (Chloromethyl)triethoxysilane / 5g / 536799853 / CS-0086574 / 0.000 / 15267-95-5 / MFCD00039354 / 212.750 / C7H17ClO3Si
eMolecules 1785665-61-3 | Medchem Express | VUF11207 (fumarate) | 5mg | 515743918 | HY-110318 | MFCD27991278 | 586.657 | C31H39FN2O8
ChemScene | Methyl 4-amino-35-dichloro-2-fluorobenzoate | 100mg | 746310752 | CS-0612352 | 2649788-83-8 | 238.040 | C8H6Cl2FNO2
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Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 2mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
Selleck Chemical LLC CarbinoxaMine Maleate S4696-100mg
Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties
Selleck Chemical LLC CA-074 methyl ester
CA-074 methyl ester (CA-074 Me Cathepsin B Inhibitor IV) is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor
eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 5g | 552720842
Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 5g | 552720842
Selleck Chemical LLC CA-074 methyl ester
CA-074 methyl ester (CA-074 Me Cathepsin B Inhibitor IV) is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor
Medchemexpress LLC HY-13251 2mg Medchemexpress, Silvestrol CAS:697235-38-4 Purity:>98%
Medchemexpress, HY-13251 2mg Silvestrol CAS:697235-38-4 Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from the fruits and twigs of Aglaia foveolata. Silvestrol induces autophagy and caspase-mediated apoptosis[2][3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.